Frontotemporal dementia and motor neuron disease
نویسندگان
چکیده
منابع مشابه
Predicting survival in frontotemporal dementia with motor neuron disease.
OBJECTIVE To determine whether clinical and demographic features are associated with prognosis in patients with frontotemporal dementia and motor neuron disease (FTD-MND). METHODS This was a case series of FTD-MND categorized according to behavioral- or language-dominant symptoms at presentation and throughout the disease course. Demographic, clinical, imaging, and survival data were analyzed...
متن کاملMotor neuron dysfunction in frontotemporal dementia.
Frontotemporal dementia and motor neuron disease share clinical, genetic and pathological characteristics. Motor neuron disease develops in a proportion of patients with frontotemporal dementia, but the incidence, severity and functional significance of motor system dysfunction in patients with frontotemporal dementia has not been determined. Neurophysiological biomarkers have been developed to...
متن کاملFrontotemporal dementia and motor neuron disease: report of 3 cases in Taiwan and literature review.
PURPOSE Case reports and a review of literature of the coexistence of motor neuron disease (MND) and frontotemporal dementia (FTD). CASE REPORT All three patients demonstrated generalized lower motor neuron signs and very few upper motor neuron signs. In the level of patterns of cognitive impairments, neuropsychological studies do not distinguish between patients with onset of weakness from b...
متن کاملSurvival profiles of patients with frontotemporal dementia and motor neuron disease.
BACKGROUND Frontotemporal dementia and amyotrophic lateral sclerosis are neurodegenerative diseases associated with TAR DNA-binding protein 43- and ubiquitin-immunoreactive pathologic lesions. OBJECTIVE To determine whether survival is influenced by symptom of onset in patients with frontotemporal dementia and amyotrophic lateral sclerosis. DESIGN, SETTING, AND PATIENTS Retrospective review...
متن کاملTDP-43 pathology in familial frontotemporal dementia and motor neuron disease without Progranulin mutations.
Frontotemporal dementia is accompanied by motor neuron disease (FTD + MND) in approximately 10% of cases. There is accumulating evidence for a clinicopathological overlap between FTD and MND based on observations of familial aggregation and neuropathological findings of ubiquitin-positive neuronal cytoplasmatic inclusions (NCI) in lower motor neurons, hippocampus and neocortex in both condition...
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ژورنال
عنوان ژورنال: Neurología (English Edition)
سال: 2010
ISSN: 2173-5808
DOI: 10.1016/s2173-5808(10)70011-0